Article

Age-related differences in the association between REM sleep and the polygenic risk for Parkinson’s disease

2025-02-06

Abstract excerpt

<h4>Objective</h4> Parkinson’s disease (PD) is one of the rare diseases for which sleep alteration is a true marker of disease outcome. Yet, how the association between sleep and PD emerges over the healthy lifetime is not established. We examined association between the polygenic risk score (PRS) for PD and the variability in the electrophysiology of Rapid Eye Movement (REM) sleep in 433 younger (18-31y) and 85...

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Literature Corpus work: a474d3f4-1670-5031-8e47-d8bd53eb6dc2
DOI: 10.1101/2025.02.05.636657

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