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Article

Alterations in sleep-activity cycles and clock gene expression across the synucleinopathy spectrum

2024-08-11

Abstract excerpt

<title>Abstract</title> <p>Background Neurodegenerative synucleinopathies including Parkinson's disease (PD) and Dementia with Lewy bodies (DLB) are strongly associated with sleep disturbances. Furthermore, isolated Rapid Eye Movement Sleep Behaviour Disorder (iRBD) is now established as the strongest risk factor for developing PD or DLB, often preceding the clinical diagnosis by several years. Objectives We ai...

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Literature Corpus work
07c553e9-9330-5ad6-8ce6-dbd1167a767a
DOI
10.21203/rs.3.rs-4717144/v1
Open publication

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Alterations in sleep-activity cycles and clock gene expression across the synucleinopathy spectrumDOI 10.21203/rs.3.rs-4717144/v1
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