Article

Wake and non-rapid eye movement sleep dysfunction is associated with colonic neuropathology in Parkinson’s disease

2023-10-04

Abstract excerpt

<h4>Study Objectives</h4> The body-first Parkinson’s disease (PD) hypothesis suggests initial gut Lewy body pathology that propagates to the pons before reaching the substantia nigra, and subsequently progresses to the diencephalic and cortical levels. This disease course may also be the most likely in PD with rapid eye movement sleep behavior disorder (RBD). <h4>Objectives</h4> We aimed to explore the potential a...

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Literature Corpus work: 93a5d66c-c1af-5f59-a1d4-67e22a3c8f9f
DOI: 10.1101/2023.10.03.23296499

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