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Article

REM sleep behavior disorder as a shared motor phenotype: A multidimensional clinical study.

Sleep medicine - 1 Jun 2026

Lanza Giuseppe, Sorte Giovanni, Bella Rita, Garifoli Angelo, Lanuzza Bartolo, Mogavero Maria P, Morreale Manuela, Pastorello Giovanni, Pennisi Manuela, Quercia Angelica, Palmigiano Aurora, Tripodi Mariangela, Pani Tapas, Antelmi Elena, Schenck Carlos H, Ferri Raffaele

Abstract excerpt

BACKGROUND: REM sleep behavior disorder (RBD) is increasingly recognized as a heterogeneous condition that may arise in different etiological contexts, including an isolated form that is often a prodromal synucleinopathy, antidepressant exposure, and RBD occurring in the context of clinically diagnosed tau-spectrum neurodegenerative syndromes. The aim of this study was to compare clinical, cognitive,...

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PMID: 41780439
DOI: 10.1016/j.sleep.2026.108880

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