Article
The challenges with the identification of Parkinson's disease subtypes.
Expert review of neurotherapeutics - 1 Feb 2026
Rigon Leonardo, Poplawska-Domaszewicz Karolina, Metta Vinod, Fogliano Carmelo, Nasi Maria Laura, Sauerbier Anna, Dafsari Haider, Leta Valentina, Falup-Pecurariu Cristian, Odin Per, Antonini Angelo, Chaudhuri Kallol Ray
Abstract excerpt
INTRODUCTION: Parkinson's disease (PD) exhibits distinct phenotypes with specific pathophysiological features. Their definition is essential to inform therapeutic choices and trials design. AREAS COVERED: We searched in September 2025 PubMed/MEDLINE, Scopus, and Web of Science to review current PD stratifications strategies based on clinical, tissue, and imaging biomarkers, highlighting their specific strengths...
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