Article

Estimating Prevalence of Human Traits Among Populations From Polygenic Risk Scores

2021-03-25

Abstract excerpt

The genetic basis of phenotypic variation across populations has not been well explained for most traits. Several factors may cause disparities, from variation in environments to divergent population genetic structure. We hypothesized that a population level polygenic risk score (PRS) can explain phenotypic variation among geographic populations based solely on risk allele frequencies. We applied a population spec...

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Literature Corpus work: 8323d854-2b7c-52c1-aad4-22d68d7fabbd
DOI: 10.21203/rs.3.rs-341766/v1

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