Article

The accuracy of polygenic score models for anthropometric traits and Type II Diabetes in the Native Hawaiian Population

2023-12-28

Abstract excerpt

Polygenic scores (PGS) are promising in stratifying individuals based on the genetic susceptibility to complex diseases or traits. However, the accuracy of PGS models, typically trained in European- or East Asian-ancestry populations, tend to perform poorly in other ethnic minority populations, and their accuracies have not been evaluated for Native Hawaiians. Using body mass index, height, and type-2 diabetes as...

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Literature Corpus work: 44b3fa47-ddd7-5f4c-ba1d-2b34be04ba80
DOI: 10.1101/2023.12.25.23300499

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