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Geographic variation and bias in polygenic scores of complex diseases and traits in Finland

2018-12-04

Abstract excerpt

Polygenic scores (PS) are becoming a useful tool to identify individuals with high genetic risk for complex diseases and several projects are currently testing their utility for translational applications. It is also tempting to use PS to assess whether genetic variation can explain a part of the geographic distribution of a phenotype. However, it is not well known how population genetic properties of the training...

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Literature Corpus work
aa2d0f83-079e-5715-941f-8cfcbedad449
DOI
10.1101/485441
Open publication

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Geographic variation and bias in polygenic scores of complex diseases and traits in FinlandDOI 10.1101/485441
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