Article

Positioning Personal Polygenic Risk score against the population background

2019-10-24

Abstract excerpt

The polygenic risk scores (PRS) approach has been widely used across different traits for estimating polygenic risk, pleiotropy and disease prediction, but mostly in European populations. The predictive ability of the PRS in non-European populations is currently limited due to the lack of genetic research performed in populations of non-European ancestry. One of the main challenges of the practical use of PRS is t...

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Literature Corpus work: e3c4b47d-e877-51cd-8af3-a35da254af51
DOI: 10.1101/813170

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