Article

Differential Results of Polygenic Risk Scoring for Multiple Sclerosis in European and African American Populations

2024-06-12

Abstract excerpt

<h4>Importance</h4> The risk of multiple sclerosis (MS) is significantly influenced by polygenic inheritance. Polygenic risk scores (PRS) for MS can help identify high-risk individuals and stratify populations for clinical trials. However, most genome-wide association studies (GWAS) have been conducted in populations of European ancestry, raising questions about the accuracy of these PRS in other ancestries. <h4>O...

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Literature Corpus work: 8a6ba051-8112-5104-ad0c-7b43017d8db3
DOI: 10.1101/2024.06.11.24308714

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