Article
Association between COMT gene polymorphisms, clinical symptoms, and cognitive functions in Han Chinese patients with schizophrenia.
Psychiatric genetics - 1 Jun 2018
Sun Zuoli, Zhang Zhengrong, Mao Peixian, Ma Yun, Li Wenbiao, Li Jun, Yang Xue, Ling Sihai, Tang Yilang
Abstract excerpt
AIM: Catechol-O-methyltransferase (COMT) gene variants may be involved in the pathogenesis of psychotic symptoms, and associated especially with negative symptom in schizophrenia, but their roles in cognitive function and treatment response remain unclear. The aim of this study was to explore the association between COMT gene polymorphisms, clinical symptoms (including cognitive function), and treatment response...
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