Article
COMT-by-sex interaction effect on psychosis proneness.
BioMed research international - 1 Jan 2015
de Castro-Catala Marta, Barrantes-Vidal Neus, Sheinbaum Tamara, Moreno-Fortuny Artal, Kwapil Thomas R, Rosa Araceli
Abstract excerpt
Schizotypy phenotypes in the general population share etiopathogenic mechanisms and risk factors with schizophrenia, supporting the notion of psychosis as a continuum ranging from nonclinical to clinical deviance. Catechol-O-methyltransferase (COMT) is a candidate susceptibility gene for schizophrenia that is involved in the regulation of dopamine in the prefrontal cortex. Several recent studies have reported a...
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