Article

The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy

2024-09-12

Abstract excerpt

N6-methyladenosine (m6A) is the most abundant and conserved transcriptional modification in eukaryotic RNA, regulating RNA fate. While the functions of m6A in the development of the mammalian brain have been extensively studied, its roles in synaptic plasticity, cognitive decline, motor function, or other brain circuits remain underexplored. To date, the role of this modification in Parkinson’s disease (PD) and ot...

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Literature Corpus work: 82882cb1-1aff-5803-a50b-cf10dcf165ed
DOI: 10.1101/2024.09.12.612649

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The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathyDOI 10.1101/2024.09.12.612649Read

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