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Altered N6-methyladenosine Modification Patterns and Transcript Profiles Contributes to Cognitive Dysfunction in High-Fat Induced Diabetic Mice

2023-12-18

Abstract excerpt

Abstract: Objectives: To establish the expression profile of N6-methyladenosine(m6A) modifications in the hippocampus of mice with diabetic cognitive impairment (DCI) and elucidate the potential regulatory mechanism. <h4>Methods:</h4> A DCI model was established by feeding a high-fat diet to C57BL/6J mice. m6A and RNA sequencing was conducted to profile the m6A-tagged transcripts in the hippocampus. <h4>Results:</...

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Literature Corpus work
1d057333-cbde-5801-9450-ed4f5fec0054
DOI
10.20944/preprints202312.1309.v1
Open publication

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Altered N6-methyladenosine Modification Patterns and Transcript Profiles Contributes to Cognitive Dysfunction in High-Fat Induced Diabetic MiceDOI 10.20944/preprints202312.1309.v1
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