Article

Rewired m6A methylation of promoter antisense RNAs in Alzheimer’s disease regulates global gene transcription in the 3D nucleome

2025-03-23

Abstract excerpt

N 6 -methyladenosine (m6A) is the most prevalent internal RNA modification that can impact mRNA expression post-transcriptionally. Recent progress indicates that m6A also acts on nuclear or chromatin-associated RNAs to impact transcriptional and epigenetic processes. However, the landscapes and functional roles of m6A in human brains and neurodegenerative diseases, including Alzheimer’s disease (AD), have been un...

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Literature Corpus work: 32afcb0d-5aaf-59dd-9b13-d66c9416dac6
DOI: 10.1101/2025.03.22.644756

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