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Synaptic m <sup>6</sup> A Epitranscriptome Reveals Functional Partitioning of Localized Transcripts for Dynamic Tripartite Synapse Modulation

2017-11-17

Abstract excerpt

A localized transcriptome at the synapse facilitates synapse-, stimulus-, and transcript-specific synthesis of the local proteome in response to neuronal activity. While enzyme-mediated mRNA modifications have been shown to regulate cellular mRNA turnover and translation, the role of these modifications in regulating synaptic RNA has not been studied. We established low-input m 6 A-seq of synaptosomal RNA to dete...

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Literature Corpus work
9e7da9bd-4d28-5a27-a8d0-6106245f2d6b
DOI
10.1101/221374
Open publication

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