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Dysregulation of RNA modification systems in clinical populations with neurocognitive disorders

22 Sept 2023

Abstract excerpt

ABSTRACT: The study of modified RNA known as epitranscriptomics has become increasingly relevant in our understanding of disease-modifying mechanisms. Methylation of N6 adenosine (m6A) and C5 cytosine (m5C) bases occur on mRNAs, tRNA, mt-tRNA, and rRNA species as well as non-coding RNAs. With emerging knowledge of RNA binding proteins that act as writer, reader, and eraser effector proteins, comes a new...

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PMID: 37905873
DOI: 10.4103/1673-5374.385858

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