Article

Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

2020-06-02

Abstract excerpt

Gene expression signatures can stratify patients with heterogeneous diseases, such as Systemic Lupus Erythematosus (SLE), yet understanding the contributions of ancestral background to this heterogeneity is not well elucidated. We hypothesized that ancestry would significantly influence gene expression signatures and measured 34 gene modules in 1566 SLE patients of african (AA), european (EA) or native american (N...

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Literature Corpus work: 8242dcd0-a016-59a8-9e24-b6f0e29778c5
DOI: 10.1101/2020.05.31.20114660

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