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Article

Identification of genetic variants in B cell expressed genes associated with systemic lupus erythematosus in African American females.

ImmunoHorizons - 10 Jul 2026

Kidwell Rachel, Gupta Mansi, Fontaine Jake, Sanz Ignacio, Scharer Christopher D

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by dysregulated B cell responses and pathogenic autoantibody production. Given the central role that B cells play in SLE pathogenesis, we aimed to characterize genetic variation within the B cell compartment of African ancestry (AFR) women with SLE who are disproportionately and more severely affected by SLE. Here, we analyzed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42479690
DOI: 10.1093/immhor/vlag029
PMCID: PMC13387164

Genes

TNFAIP3

Provenance

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