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Article

Deconvoluting the heterogeneity of SLE: The contribution of ancestry.

The Journal of allergy and clinical immunology - 1 Jan 2022

Owen Katherine A, Grammer Amrie C, Lipsky Peter E

Abstract excerpt

Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disorder with a prominent genetic component. Evidence has shown that individuals of non-European ancestry experience the disease more severely, exhibiting an increased incidence of cardiovascular disease, renal involvement, and tissue damage compared with European ancestry populations. Furthermore, there seems to be variability in the response of...

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Environment
Epigenesis, Genetic
Genetic Predisposition to Disease
Genomics
Lupus Erythematosus, Systemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Monoclonal and Polyclonal Antibodies Research

Systemic Lupus Erythematosus Research

T-cell and B-cell Immunology

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Identifiers

PMID: 34857396
DOI: 10.1016/j.jaci.2021.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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