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Article

Genetic ancestry, serum interferon-α activity, and autoantibodies in systemic lupus erythematosus.

The Journal of rheumatology - 1 Jun 2012

Ko Kichul, Franek Beverly S, Marion Miranda, Kaufman Kenneth M, Langefeld Carl D, Harley John B, Niewold Timothy B

Abstract excerpt

OBJECTIVE: To investigate and refine the relationships among systemic lupus erythematosus (SLE) and related autoantibodies, interferon-α (IFN-α), and various ancestral backgrounds. METHODS: We investigated quantitatively defined genetic ancestry through principal component analysis in place of self-reported ancestry. RESULTS: African ancestry was found to be associated with presence of anti-RNP antibody (p =...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22505704
DOI: 10.3899/jrheum.111467
PMCID: PMC3381952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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