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Article

The genetics and molecular pathogenesis of systemic lupus erythematosus (SLE) in populations of different ancestry.

Gene - 20 Aug 2018

Goulielmos George N, Zervou Maria I, Vazgiourakis Vassilis M, Ghodke-Puranik Yogita, Garyfallos Alexandros, Niewold Timothy B

Abstract excerpt

Systemic lupus erythematosus (SLE; OMIM 152700) is a highly heterogeneous disorder, characterized by differences in autoantibody profile, serum cytokines, and a multi-system involvement commonly affecting the skin, renal, musculoskeletal, and hematopoetic systems clinical manifestations involving. Disease features range from mild manifestations, such as rash or arthritis, to life-threatening end-organ...

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PMID: 29775752
DOI: 10.1016/j.gene.2018.05.041

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