Article

Ancestry-based differences in the immune system are associated with lupus severity

2021-12-29

Abstract excerpt

<title>Abstract</title> <p>Systemic lupus erythematosus (SLE) affects 1 in 537 of African American (AA) women, which is >2-fold more than European American (EA) women. AA patients also develop the disease at a younger age, have more severe symptoms, and a greater chance of early mortality. We used a multi-omics approach to uncover ancestry-specific immune alterations in SLE patients and healthy controls that may...

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Literature Corpus work: 201b2c37-cbbb-5aff-8389-a5990ac9e88f
DOI: 10.21203/rs.3.rs-1149629/v1

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