Article

Genetic impacts on within-pair DNA methylation variance in monozygotic twins capture gene-environment interactions and cell-type effects

2025-06-21

Abstract excerpt

<h4>Background</h4> Genetic variants that are associated with phenotypic variability, or variance quantitative trait loci (vQTLs), have been detected for multiple human traits. Gene-environment interactions can lead to differential phenotypic variability across genotype groups, therefore, genetic variants that interact with environmental exposures can manifest as vQTLs. Although changes in DNA methylation variabi...

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Literature Corpus work: 81edf2ac-e0e6-5dde-834e-8dd601d14189
DOI: 10.1101/2025.06.17.659865

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