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Article

Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

2021-05-30

Abstract excerpt

<h4>Background</h4> Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease. There is a need for systematic approaches not only for determining methylation quantitative trait loci (methQTL) but also for discriminating general from cell-type-specific effects. <h4>Results</h4> Here, we present a two-step computational fra...

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Literature Corpus work
1a69fb29-7017-5774-af86-a895bd738ea8
DOI
10.1101/2021.05.30.445237
Open publication

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Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGARDOI 10.1101/2021.05.30.445237
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