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Glucose selectively drives a rapid oxidative burst and immunometabolic reprogramming in human neutrophils during <i>Mycobacterium tuberculosis</i> infection

2026-05-07

Abstract excerpt

Neutrophil functions have been linked to tuberculosis (TB)-associated tissue damage; however, the mechanisms driving immunopathology in the human TB lung remain poorly understood, due partly to the scarcity of human tissue for study. Here, we examine the metabolic and bioenergetic reprogramming of human neutrophils in response to Mycobacterium tuberculosis ( Mtb ) infection. In human necrotic TB granulomas, leve...

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Literature Corpus work
816d31c0-e8ac-5e8d-9d95-6702fd23f758
DOI
10.64898/2026.05.05.722986
Open publication

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Glucose selectively drives a rapid oxidative burst and immunometabolic reprogramming in human neutrophils during <i>Mycobacterium tuberculosis</i> infectionDOI 10.64898/2026.05.05.722986
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