Article

<i>M. bovis</i> PPD Enhances Respiratory Bioenergetics of Human vs. Bovine Macrophages

2024-03-04

Abstract excerpt

The role of macrophage (MØ) cellular metabolism and reprogramming during TB infection is of great interest due to the influence of Mycobacterium spp. on MØ bioenergetics. Recent studies have shown that M. tuberculosis induces a TLR2-dependent shift towards aerobic glycolysis and metabolic reprogramming, comparable to the established LPS induced pro-inflammatory M1 MØ polarisation. Distinct differences in the met...

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Literature Corpus work: e1c9aa4c-54a7-5f53-a2f0-7b879c0e1d20
DOI: 10.1101/2024.02.29.582730

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