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<i>Mycobacterium tuberculosis</i> Modulates the Metabolism of Alternatively Activated Macrophages to Promote Foam Cell Formation and Intracellular Survival

2019-12-14

Abstract excerpt

<h4>ABSTRACT</h4> The ability of Mycobacterium tuberculosis (Mtb) to persist inside host cells relies on metabolic adaptation, like the accumulation of lipid bodies (LBs) in the so-called foamy macrophages (FM). Indeed, FM are favorable to Mtb. The activation state of macrophages is tightly associated to different metabolic pathways, such as lipid metabolism, but whether differentiation towards FM differs between...

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Literature Corpus work
6d9c2a74-1eb8-5050-ac50-d630e31caeac
DOI
10.1101/2019.12.13.876300
Open publication

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