Article

Neutrophil-primed immunopathology in poorly-controlled diabetes worsens matrix destruction in pulmonary tuberculosis

2026-05-26

Abstract excerpt

<h4>Background</h4> Diabetes mellitus (DM) worsens pulmonary tuberculosis (TB) and drives systemic hyper-inflammation, but the underlying mechanisms remain unknown. Neutrophils have key roles in TB immunopathology and lung cavitation. Here, we determine the role of neutrophils in DMTB patients and in driving TB immunopathology. <h4>Methods</h4> Sputum and plasma from 30 TB and 30 DMTB patients were analysed for...

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Literature Corpus work: 64737aae-7e87-5fa0-8dc9-46fd8e5c7003
DOI: 10.64898/2026.05.24.26353970

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