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Investigation into germ cell fate determination of rat embryonic stem cells

2020-01-01

Abstract excerpt

The laboratory rat is an important experimental model in biomedical research. Rat embryonic stem cells (ESCs) are valuable for studying mammalian development and for facilitating germ line-modification of rat strains. However, the germline contribution of rat ESCs when injected into developing rat embryos can be variable, restricting their utility. This investigation addressed two key questions; could rat ESC diff...

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Literature Corpus work
80b5921c-263e-5815-a0dd-76ea91338467
DOI
10.7488/era/281
Open publication

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