Article
Rat bone marrow derived mesenchymal progenitor cells support mouse ES cell growth and germ-like cell differentiation.
Cell biology international - 1 Mar 2009
Cui Guanghui, Qi Zhengyu, Guo Xin, Qin Jie, Gui Yaoting, Cai Zhiming
Abstract excerpt
Mouse embryonic fibroblasts (MEFs) have been used as feeder cells to support the growth of mouse embryonic stem cell (mESC) and primordial germ cells (PGC) in culture for many years. However, MEF preparation is a complex and tedious task. Recently, there are reports indicating that the microenvironment provided by bone marrow stromal cells could support the survival of embryonic-like stem cells in bone marrow. In...
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