Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional primordial germ cell–like cells from pluripotent stem cells in rats

7 Apr 2022

Abstract excerpt

The in vitro generation of germ cells from pluripotent stem cells (PSCs) can have a substantial effect on future reproductive medicine and animal breeding. A decade ago, in vitro gametogenesis was established in the mouse. However, induction of primordial germ cell-like cells (PGCLCs) to produce gametes has not been achieved in any other species. Here, we demonstrate the induction of functional PGCLCs from rat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35389778
DOI: 10.1126/science.abl4412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional primordial germ cell–like cells from pluripotent stem cells in ratsPMID 35389778Read ↗

Germline specification from pluripotent stem cellsSemantic proximity Read ↗

In vitro gametogenesis from embryonic stem cells in livestock species: recent advances, opportunities, and challenges to overcomeSemantic proximity Read ↗

Research Advances in Gametogenesis and Embryogenesis Using Pluripotent Stem CellsSemantic proximity Read ↗

Primordial Germ Cells: Current Knowledge and PerspectivesSemantic proximity Read ↗

Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem CellsSemantic proximity Read ↗

Generation of germ cells from pluripotent stem cells in mammalsSemantic proximity Read ↗

Spermatogenesis from epiblast and primordial germ cells following transplantation into postnatal mouse testis.Semantic proximity Read ↗

Mammalian in vitro gametogenesisSemantic proximity Read ↗

Roadmap of germline development and in vitro gametogenesis from pluripotent stem cellsSemantic proximity Read ↗

Generation of Functional Oocytes and Spermatids from Fetal Primordial Germ Cells after Ectopic Transplantation in Adult MiceSemantic proximity Read ↗

Offspring from Oocytes Derived from in Vitro Primordial Germ Cell–like Cells in MiceSemantic proximity Read ↗

In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.