Article

Melatonin Maintains Macrophage M1 Phenotype to Reverse LPS-stimulated Tumor Immune Tolerance

2020-06-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Lipopolysaccharide (LPS) is a potent trigger of macrophage-mediated inflammation and its repeated stimulation results in immune tolerance. This study is to explore the cellular mechanisms of LPS-mediated tumor immune tolerance and to investigate whether melatonin can reverse this tolerance. <bold>Methods:</bold> The effect of melatonin and LPS on macrophages was...

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Literature Corpus work: 80a5a619-e987-5841-bcaa-9b11cb1b35e5
DOI: 10.21203/rs.3.rs-37928/v1

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