Article
Macrophage Polarization and Its Role in Liver Disease.
Frontiers in immunology - 1 Jan 2021
Wang Cheng, Ma Cheng, Gong Lihong, Guo Yuqin, Fu Ke, Zhang Yafang, Zhou Honglin, Li Yunxia
Abstract excerpt
Macrophages are important immune cells in innate immunity, and have remarkable heterogeneity and polarization. Under pathological conditions, in addition to the resident macrophages, other macrophages are also recruited to the diseased tissues, and polarize to various phenotypes (mainly M1 and M2) under the stimulation of various factors in the microenvironment, thus playing different roles and functions. Liver...
Topics
- Animals
- Biomarkers
- Cell Differentiation
- Cell Plasticity
- Diagnosis, Differential
- Disease Susceptibility
- Energy Metabolism
- Gene Expression Regulation
- Humans
- Liver Diseases
- Macrophage Activation