Article
Phenotypic comparison and the potential antitumor function of immortalized bone marrow-derived macrophages (iBMDMs).
Frontiers in immunology - 1 Jan 2024
Xie Dong-Kun, Yao Jin, Li Peng-Hui, Zhu Yan-Wen, Chen Jia-Nuo, Cao Xiu-Li, Cheng Shi-Lin, Chen Ya-Miao, Huang Yi-Fei, Wang Liang, Wang Zan-Han, Qiao Rong, Ge Jia-Mei, Yue Huan, Wei Li, Liu Zhong-Yuan, Han Hua, Qin Hong-Yan, Zhao Jun-Long
Abstract excerpt
Introduction: Macrophages are an important component of innate immunity and involved in the immune regulation of multiple diseases. The functional diversity and plasticity make macrophages to exhibit different polarization phenotypes after different stimuli. During tumor progression, the M2-like polarized tumor-associated macrophages (TAMs) promote tumor progression by assisting immune escape, facilitating tumor...
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