Article
Macrophage phenotype-switching in cancer.
European journal of pharmacology - 15 Sept 2022
Zhang Jiamin, Zhou Xiaoyan, Hao Hua
Abstract excerpt
Tumour-associated macrophages (TAMs) have been found to be of great importance in tumorigenesis and in promoting malignant progression, including tumour angiogenesis and metastasis. Moreover, the TAM phenotype is more likely to be an M2 type. Transforming TAMs by M2-polarization into the tumour-suppressive M1-phenotype is an important approach for tumour therapy. In this review, we analysed the effects of the...
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