Article
Exosomal miRNAs-mediated macrophage polarization and its potential clinical application.
International immunopharmacology - 1 Apr 2023
Yu Ming Yun, Jia Hui Jie, Zhang Jing, Ran Guang He, Liu Yan, Yang Xiu Hong
Abstract excerpt
Macrophages are highly heterogeneous and plastic immune cells that play an important role in the fight against pathogenic microorganisms and tumor cells. After different stimuli, macrophages can polarize to the M1 phenotype to show a pro-inflammatory effect and the M2 phenotype to show an anti-inflammatory effect. The balance of macrophage polarization is highly correlated with disease progression, and...
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