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Article

Polysaccharides of Brassica rapa L. attenuate tumor growth via shifting macrophages to M1-like phenotype.

Phytotherapy research : PTR - 1 Oct 2022

Guo Weiwei, Liu Xiujun, Guo Junting, Gao Ruijuan, Xiang Xiaodong, An Xiqiang, Bai Liping

Abstract excerpt

Macrophages are the major tumor-infiltrating leukocytes, and tumor-associated macrophages (TAM) play a critical role in cancer-related inflammation since they show alternative polarization to M1 (tumor-inhibited macrophages) or M2 (tumor-promoted macrophages) phenotype. Brassica rapa L. (B. rapa) has been clinically proven to have anti-tumor and immunity-enhancing activity, and the polysaccharides of B. rapa...

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PMID: 35766285
DOI: 10.1002/ptr.7545

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