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Article

Codonopsis pilosula-derived glycopeptide dCP1 promotes the polarization of tumor-associated macrophage from M2-like to M1 phenotype.

Cancer immunology, immunotherapy : CII - 14 May 2024

Liu Hongxu, Yao Maojin, Ren Jiaoyan

Abstract excerpt

The majority of the immune cell population in the tumor microenvironment (TME) consists of tumor-associated macrophages (TAM), which are the main players in coordinating tumor-associated inflammation. TAM has a high plasticity and is divided into two main phenotypes, pro-inflammatory M1 type and anti-inflammatory M2 type, with tumor-suppressive and tumor-promoting functions, respectively. Considering the...

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Identifiers

PMID: 38743074
DOI: 10.1007/s00262-024-03694-6
PMCID: PMC11093951

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