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Article

Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta.

American journal of human genetics - 3 Nov 2016

Hamada Hirotaka, Okae Hiroaki, Toh Hidehiro, Chiba Hatsune, Hiura Hitoshi, Shirane Kenjiro, Sato Tetsuya, Suyama Mikita, Yaegashi Nobuo, Sasaki Hiroyuki, Arima Takahiro

Abstract excerpt

DNA methylation is globally reprogrammed after fertilization, and as a result, the parental genomes have similar DNA-methylation profiles after implantation except at the germline differentially methylated regions (gDMRs). We and others have previously shown that human blastocysts might contain thousands of transient maternally methylated gDMRs (transient mDMRs), whose maternal methylation is lost in embryonic...

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Identifiers

PMID: 27843122
DOI: 10.1016/j.ajhg.2016.08.021
PMCID: PMC5097938

Genes

KLHDC10
PROSER2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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