Article

Atlas of imprinted and allele-specific DNA methylation in the human body

2024-05-02

Abstract excerpt

Allele-specific DNA methylation, determined genetically or epigenetically, is involved in gene regulation and underlies multiple pathologies. Yet, our knowledge of this phenomenon is partial, and largely limited to blood lineages. Here, we present a comprehensive atlas of allele-specific DNA methylation, using deep whole-genome sequencing across 39 normal human cell types. We identified 325k genomic regions, cover...

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Literature Corpus work: f9f241db-42ee-53e0-ab39-e7f2508cf9cc
DOI: 10.1101/2024.05.01.591988

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