Article

Whole Genome Bisulfite Sequencing of Cell Free DNA and its Cellular Contributors Uncovers Placenta Hypomethylated Domains

2014-04-11

Abstract excerpt

<h4>Background: </h4> Circulating cell free fetal DNA has enabled non-invasive prenatal fetal aneuploidy testing without direct discrimination of the genetically distinct maternal and fetal DNA. Current testing may be improved by specifically enriching the sample material for fetal DNA. DNA methylation may allow for such a separation of DNA and thus support additional clinical opportunities; however, this depends...

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Literature Corpus work: c1c6ffb3-ec0c-53b0-a6e0-2c273058c416
DOI: 10.1101/004101

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