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Human placental methylome in the interplay of adverse placental health, environmental exposure, and pregnancy outcome

1 Aug 2019

Abstract excerpt

The placenta is the interface between maternal and fetal circulations, integrating maternal and fetal signals to selectively regulate nutrient, gas, and waste exchange, as well as secrete hormones. In turn, the placenta helps create the in utero environment and control fetal growth and development. The unique epigenetic profile of the human placenta likely reflects its early developmental separation from the...

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PMID: 31369552
DOI: 10.1371/journal.pgen.1008236

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