Article
Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian Placentas
4 Aug 2015
Abstract excerpt
Over the last 20-80 million years the mammalian placenta has taken on a variety of morphologies through both divergent and convergent evolution. Recently we have shown that the human placenta genome has a unique epigenetic pattern of large partially methylated domains (PMDs) and highly methylated domains (HMDs) with gene body DNA methylation positively correlating with level of gene expression. In order to...
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