Article

Family history and polygenic risk of cardiovascular disease: independent factors associated with secondary cardiovascular events in patients undergoing carotid endarterectomy

2019-09-18

Abstract excerpt

<h4>Background</h4> Family history (FHx) of cardiovascular disease (CVD) is a risk factor for CVD and a proxy for cardiovascular heritability. Polygenic risk scores (PRS) summarizing >1 million variants for coronary artery disease (CAD) are associated with incident and recurrent CAD events. However, little is known about the influence of FHx or PRS on secondary cardiovascular events (sCVE) in patients undergoing c...

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Literature Corpus work: 8012738f-d29a-5c7f-ae46-d34c48c8aca5
DOI: 10.1101/19006718

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