Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic risk scores reveal shared polygenic risk across five common cardiovascular diseases.

Atherosclerosis - 1 Jun 2026

Adane Tigist D, Sedaghati-Khayat Bahar, Trap Lianne, Dagnaw Asrat B, Kavousi Maryam, Rivadeneira Fernando, van Meurs Joyce B J, Uitterlinden André G, van Rooij Jeroen G J

Abstract excerpt

BACKGROUND AND AIM: The five cardiovascular diseases (CVDs): Coronary artery disease (CAD), stroke, heart failure (HF), peripheral arterial disease (PAD), and atrial fibrillation(Afib) often co-occur. Most polygenic risk scores (PRSs) are developed for individual CVDs, limiting their clinical utility across multiple CVDs. We investigated associations between five PRSs and (1) their CVDs, (2) cross-disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrial Fibrillation
Share to Genetic Risk Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Disease Risk Factors

Share to Heart Failure

Share to Multifactorial Inheritance

Share to Peripheral Arterial Disease

Share to Stroke

Share to UK Biobank

Source

Identifiers

PMID: 42096872
DOI: 10.1016/j.atherosclerosis.2026.120763

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic risk scores reveal shared polygenic risk across five common cardiovascular diseases.PMID 42096872Read ↗

Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease: A clinical consensus statement of the ESC Council on Cardiovascular Genomics, the ESC Cardiovascular Risk Collaboration, and the European Association of Preventive CardiologySemantic proximity Read ↗

A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.Semantic proximity Read ↗

Risk prediction for cardiovascular related diseases using PRS and EHR in the Framingham Heart Study.Semantic proximity Read ↗

Polygenic Risk Scores in Coronary Artery Disease and Atrial Fibrillation.Semantic proximity Read ↗

Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement From the American Heart Association.Semantic proximity Read ↗

Polygenic risk scores in coronary artery disease.Semantic proximity Read ↗

Risk Prediction Using Polygenic Risk Scores for Prevention of Stroke and Other Cardiovascular Diseases.Semantic proximity Read ↗

Bridging traditional risk factors and genetic insights: A review on polygenic risk scores in cardiovascular diseasesSemantic proximity Read ↗

Broad Clinical Manifestations of Polygenic Risk for Coronary Artery Disease in the Women’s Health InitiativeSemantic proximity Read ↗

Current State and Future of Polygenic Risk Scores in Cardiometabolic Disease: A Scoping Review.Semantic proximity Read ↗

Polygenic risk of cardiovascular disease manifests in cardiac structure and functionSemantic proximity Read ↗

Polygenic Risk Scores: The Next Step for Improved Risk Stratification in Coronary Artery Disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.