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Article

Prioritizing acquired risk factors of atherosclerotic cardiovascular disease according to genetic predisposition: implications for precise prevention.

BMC cardiovascular disorders - 3 Dec 2025

Zhang Ruiqi, Xiang Boyang, Zhou Yujia, Li Chunhong, Chen Xuelian, Zhu Shushu

Abstract excerpt

BACKGROUND: Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death worldwide. This study aimed to investigate the contributions of acquired risk factors to ASCVD across different genetic risk groups. METHODS: This study included 430,191 participants aged 40 - 69 from the UK Biobank cohort. Population-attributable fractions (PAFs) of 25 acquired risk factors (including four socioeconomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41339782
DOI: 10.1186/s12872-025-05312-4
PMCID: PMC12676810

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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