Article

Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolution

2024-06-01

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and causes significant morbidity, ultimately leading to end-stage kidney disease. PKD pathogenesis is characterized by complex and dynamic alterations in multiple cell types during disease progression, hampering a deeper understanding of disease mechanism and the development of therapeutic approaches. Here, we generat...

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Literature Corpus work: d35b4c37-282a-510d-a363-39984a0d73e4
DOI: 10.1101/2024.05.27.595830

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