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Multi-omic profiling of human antibody-secreting cells reveals diverse subsets sustain durable humoral immunity

2026-04-17

Abstract excerpt

<h4>ABSTRACT</h4> Antibody-secreting cells (ASCs) provide humoral immunity that can mediate lifelong protection against pathogens. Current classifications cannot delineate the heterogenous functionalities, tissue residencies, and lifespans of human ASC subsets, impeding clinical translation. We applied multi-omic sequencing, spatial proteomics, and functional assays to discover and characterize human bone marrow...

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Literature Corpus work
7e418bd8-1a09-5740-8534-b347fd5372a2
DOI
10.64898/2026.04.13.717827
Open publication

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Multi-omic profiling of human antibody-secreting cells reveals diverse subsets sustain durable humoral immunityDOI 10.64898/2026.04.13.717827
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