Article
Targeting plasma cells: are we any closer to a panacea for diseases of antibody-secreting cells?
Immunological reviews - 1 Mar 2016
Low Michael, Infantino Simona, Grigoriadis George, Tarlinton David
Abstract excerpt
Antibody-secreting cells (ASCs) are critical for a functional and effective adaptive immune system. In a number of illnesses, however, these same cells contribute to the underlying disease state leading to significant morbidity and mortality. While therapeutic targeting of antibody-secreting cells has progressed significantly over the last two decades, many of these conditions remain major health problems. In...
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